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Tetracyclines also bind to the uptake is decreased by the calcium ions in dairy products, so they should not be taken together. Tetracyclines accumulate in tooth enamel and bone and are not recommended for use in children because they cause discolouration of the teeth and stunt bone growth. Resistance to tetracyclines is common due to decreased accumulation in bacterial cells. Because of this, broad-spectrum use of tetracyclines has declined and they are now used mainly to treat chlamydia infections, Lyme disease and acne. Adverse effects of tetracyclines include nausea, vomiting, diarrhoea and liver toxicity. People with myasthenia gravis or systemic lupus erythematosus should not use tetracyclines because they can exacerbate these diseases.

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  • Table 1 left panel, for example acrivastine.
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The reasons for this are not know, but suggestions include nicotine induction of detoxifying enzymes, inhibition of harmful enzymes or stimulation of factors that protect neurons. Treatment of Parkinsons disease is not usually started until symptoms are interfering with daily life and should be initiated under supervision of a specialist.

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