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Spironolactone is a potassium sparing diuretic like eplerenone that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered. |
ALDACTONE is indicated as add-on therapy for the treatment of hypertension, to lower blood pressure in patients who are not adequately controlled on other agents. Patients who develop hyperkalemia on 25 mg once daily may have their dosage reduced to 25 mg every other day see Warnings and Precautions 5. |
Spironolactone is used to treat fluid retention oedema caused by liver disease, kidney problems or heart failure. Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. |
Spironolactone belongs to the class of medications known as diuretics water pills. Myths: Pneumococcal disease. |
It is expressed in normal mucosal cells and is overexpressed in adenocarcinoma, aldactone a 25 mg espironolactona especially colon cancer. |
Potassium-sparing diuretic; used for edema, ascites, HTN, hypokalemia, acne vulgaris, polycystic ovary syndrome, female hirsutism, and to diagnose primary hyperaldosteronism; also improves survival and NYHA functional class, and reduces hospitalizations in NYHA Class IV heart failure. |
Spironolactone is used to treat fluid retention oedema caused by liver disease, kidney problems or heart failure. Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. |
Minutes later, however, a more acute feeling surfaced, one that can really only be described as the pain of a million little tiny cheapo earrings pricking my guts. The pain subsided. |
Children should only be treated under guidance of a paediatric specialist. |
The dose for treating high blood pressure hypertension is 50 to mg daily in single or divided doses. |