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Lamotrigine 3,5-diamino 2,3-dicholorophenyl -1,2,4-triazine is a phenyyltriazine with a molecular weight of From: Handbook of Clinical Neurology, |
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Lamotrigine may cause a severe or life-threatening skin rash, especially in children and in people who take a very high starting dose, or those who also take valproic acid Depakene or divalproex Depakote. |
Serious rashes requiring hospitalization including Stevens-Johnson syndrome and discontinuation of treatment have occurred in 0. Almost all life-threatening rashes have occurred within 2- 8 weeks of lamotrigine therapy, but they have also occurred after prolonged treatment; duration cannot be relied on as a means to predict the potential risk heralded by the first appearance of a rash. |
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