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Valproic acid VPA is a broad-spectrum, carboxylic acid-derived anticonvulsant that has been used in the treatment of epilepsy, bipolar disease, schizophrenia, and migraine headache. Its main mechanism of action is not well understood, but it is thought that it increases the amount of the inhibitory neurotransmitter, gamma-aminobutyric acid GABA, in the central nervous system CNS. |
A year-old male with a history of bipolar disorder is brought in by ambulance for altered mental status. |
Take this medicine only as directed by your doctor to help your condition as much as possible and to decrease the chance of unwanted effects. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. |
Complex partial seizures: Indicated as monotherapy and adjunctive therapy for complex partial seizures that occur either in isolation or in association with other types of seizures. |
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in by Beverly S. |
General Population: Hepatic failure resulting in fatalities has occurred in patients receiving valproate and its derivatives. These incidents usually have occurred during the first six months of treatment. |
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Pharmacological treatment of impulsivity and aggressive behavior. |









